diff --git a/src/app/components/network/network-legend/network-legend.component.html b/src/app/components/network/network-legend/network-legend.component.html
index 23d414745c825e83552781b7460449f6c045427f..356cb1826846832cf03c2ce05cd98c519b7b08bc 100644
--- a/src/app/components/network/network-legend/network-legend.component.html
+++ b/src/app/components/network/network-legend/network-legend.component.html
@@ -1,7 +1,7 @@
 <div
   class="legend"
   [class.right]="config.legendPos === 'right'"
-  [ngClass]="{ 'legend-small': drugstoneConfig.smallStyle }"
+  [ngClass]="{ 'legend-small': drugstoneConfig.smallStyle, 'expression': networkHandler.activeNetwork.currentViewSelectedTissue }"
 >
   <div class="legend-background" *ngIf="!config.legendUrl.length"></div>
   <!-- default legend in html -->
@@ -12,90 +12,105 @@
           class="list-item"
           *ngIf="nodeGroup.key && checkNodeGroupContext(nodeGroup.key)"
         >
-          <ng-container *ngIf="nodeGroup.value.image">
-            <!-- group icon given, use icon in legend -->
+          <!-- special legend for node types concerned by expression -->
+          <ng-container *ngIf="networkHandler.activeNetwork.nodeGroupsWithExpression.has(nodeGroup.key)">
             <th>
-              <img [src]="nodeGroup.value.image" class="legend-icon" />
-            </th>
-            <td class="group-name">&nbsp;{{ nodeGroup.value.groupName }}</td>
-          </ng-container>
-
-          <ng-container
-            *ngIf="!nodeGroup.value.image"
-            [ngSwitch]="nodeGroup.value.shape"
-          >
-            <!-- no image given, create icon programmatically -->
-            <th *ngSwitchCase="'text'">
-              <span class="node text"> text </span>
-            </th>
-            <th *ngSwitchCase="'hexagon'">
-              <span
-                class="node hexagon"
-                [style.color]="nodeGroup.value.color.background"
-              >
-                &#x2B23;
-              </span>
-            </th>
-            <th *ngSwitchCase="'triangle'">
-              <span
-                class="node triangle"
-                [style.border-bottom-color]="nodeGroup.value.color.background"
-              >
-              </span>
-            </th>
-            <th *ngSwitchCase="'triangleDown'">
-              <span
-                class="node triangleDown"
-                [style.border-top-color]="nodeGroup.value.color.background"
-              >
-              </span>
-            </th>
-            <th *ngSwitchCase="'diamond'">
               <span
-                class="node diamond"
+                class="node dot expression-style"
                 [style.background-color]="nodeGroup.value.color.background"
               >
               </span>
             </th>
-            <th *ngSwitchCase="'star'">
-              <span
-                class="node star"
-                [style.border-bottom-color]="nodeGroup.value.color.background"
-                [style.color]="nodeGroup.value.color.background"
-              >
-              </span>
-            </th>
-            <th *ngSwitchCase="'circle'">
-              <span
-                class="node circle"
-                [style.background-color]="nodeGroup.value.color.background"
-                [style.color]="nodeGroup.value.font.color"
-              >
-                <span style="padding-top: 1px">
-                ...
-                  </span>
-              </span>
-            </th>
-            <th *ngSwitchCase="'ellipse'">
-              <span
-                class="node ellipse"
-                [style.background-color]="nodeGroup.value.color.background"
-              >
-              </span>
-            </th>
-            <th *ngSwitchDefault>
-              <span
-                class="node {{ nodeGroup.value.shape }}"
-                [style.background-color]="nodeGroup.value.color.background"
-              >
-              </span>
-            </th>
-            <td class="group-name">&nbsp;{{ nodeGroup.value.groupName }}</td>
+            <td class="group-name">&nbsp;{{ nodeGroup.value.groupName }} (exprs)</td>
+          </ng-container>
+
+          <!-- normal legend without expression -->
+          <ng-container *ngIf="!networkHandler.activeNetwork.nodeGroupsWithExpression.has(nodeGroup.key)">
+            <ng-container *ngIf="nodeGroup.value.image">
+              <!-- group icon given, use icon in legend -->
+              <th>
+                <img [src]="nodeGroup.value.image" class="legend-icon" />
+              </th>
+              <td class="group-name">&nbsp;{{ nodeGroup.value.groupName }}</td>
+            </ng-container>
+
+            <ng-container
+              *ngIf="!nodeGroup.value.image"
+              [ngSwitch]="nodeGroup.value.shape"
+            >
+              <!-- no image given, create icon programmatically -->
+              <th *ngSwitchCase="'text'">
+                <span class="node text"> text </span>
+              </th>
+              <th *ngSwitchCase="'hexagon'">
+                <span
+                  class="node hexagon"
+                  [style.color]="nodeGroup.value.color.background"
+                >
+                  &#x2B23;
+                </span>
+              </th>
+              <th *ngSwitchCase="'triangle'">
+                <span
+                  class="node triangle"
+                  [style.border-bottom-color]="nodeGroup.value.color.background"
+                >
+                </span>
+              </th>
+              <th *ngSwitchCase="'triangleDown'">
+                <span
+                  class="node triangleDown"
+                  [style.border-top-color]="nodeGroup.value.color.background"
+                >
+                </span>
+              </th>
+              <th *ngSwitchCase="'diamond'">
+                <span
+                  class="node diamond"
+                  [style.background-color]="nodeGroup.value.color.background"
+                >
+                </span>
+              </th>
+              <th *ngSwitchCase="'star'">
+                <span
+                  class="node star"
+                  [style.border-bottom-color]="nodeGroup.value.color.background"
+                  [style.color]="nodeGroup.value.color.background"
+                >
+                </span>
+              </th>
+              <th *ngSwitchCase="'circle'">
+                <span
+                  class="node circle"
+                  [style.background-color]="nodeGroup.value.color.background"
+                  [style.color]="nodeGroup.value.font.color"
+                >
+                  <span style="padding-top: 1px">
+                  ...
+                    </span>
+                </span>
+              </th>
+              <th *ngSwitchCase="'ellipse'">
+                <span
+                  class="node ellipse"
+                  [style.background-color]="nodeGroup.value.color.background"
+                >
+                </span>
+              </th>
+              <th *ngSwitchDefault>
+                <span
+                  class="node {{ nodeGroup.value.shape }}"
+                  [style.background-color]="nodeGroup.value.color.background"
+                >
+                </span>
+              </th>
+              <td class="group-name">&nbsp;{{ nodeGroup.value.groupName }}</td>
+            </ng-container>
           </ng-container>
         </tr>
       </ng-container>
     </ng-container>
-
+    
     <ng-container *ngIf="config.showLegendEdges && !_emptyEdgeConfig">
       <tr
         *ngFor="let edgeGroup of config.edgeGroups | keyvalue"
diff --git a/src/app/components/network/network-legend/network-legend.component.scss b/src/app/components/network/network-legend/network-legend.component.scss
index acd385d9e4ee6ce0d1b29e81807276c42a0101f9..6b095e055153bfb988a9c964fb70c0d0e0f9ccb6 100644
--- a/src/app/components/network/network-legend/network-legend.component.scss
+++ b/src/app/components/network/network-legend/network-legend.component.scss
@@ -85,13 +85,20 @@ div.legend {
         border-radius: 50%;
         display: inline-block;
       }
-      .dot {
+      .dot:not(.expression-style) {
         background: $legend-default-background-color;
         border-radius: 50%;
         width: $legend-circle-size;
         height: $legend-circle-size;
         display: inline-block;
       }
+      .dot.expression-style {
+        background: conic-gradient(rgba(255, 255, 255, .6) 0.00% 25.00%, rgba(255, 255, 255, .0) 25.00% 40.00%, rgba(255, 255, 255, .6) 40.00%);
+        border-radius: 50%;
+        width: $legend-circle-size;
+        height: $legend-circle-size;
+        display: inline-block;
+      }
       .circle {
         background: $legend-default-background-color;
         border-radius: 50%;
diff --git a/src/app/components/network/network-legend/network-legend.component.ts b/src/app/components/network/network-legend/network-legend.component.ts
index 7fc7c10b4401e87e6c924c6055d88c0acf8622b8..7db97954f5b657540dcefd913dfb105f0574eb92 100644
--- a/src/app/components/network/network-legend/network-legend.component.ts
+++ b/src/app/components/network/network-legend/network-legend.component.ts
@@ -3,6 +3,7 @@ import { LegendContext } from 'src/app/interfaces';
 import { DrugstoneConfigService } from 'src/app/services/drugstone-config/drugstone-config.service';
 import {IConfig} from '../../../config';
 import {LegendService} from "src/app/services/legend-service/legend-service.service";
+import { NetworkHandlerService } from 'src/app/services/network-handler/network-handler.service';
 
 @Component({
   selector: 'app-network-legend',
@@ -46,7 +47,7 @@ export class NetworkLegendComponent implements OnInit {
     return Object.keys(this.config.edgeGroups).some(key => this.checkEdgeGroupContext(key));
   }
 
-  constructor(public drugstoneConfig: DrugstoneConfigService, public legendService: LegendService) { }
+  constructor(public drugstoneConfig: DrugstoneConfigService, public legendService: LegendService, public networkHandler: NetworkHandlerService) { }
 
   ngOnInit(): void {
   }
diff --git a/src/app/components/network/network.component.ts b/src/app/components/network/network.component.ts
index cdcee9ae5ff828862459bb395868f63a316c76c4..afed865d1b04cc43ef199c7afff18066d3878622 100644
--- a/src/app/components/network/network.component.ts
+++ b/src/app/components/network/network.component.ts
@@ -85,6 +85,8 @@ export class NetworkComponent implements OnInit {
 
   public loading = false;
 
+  public nodeGroupsWithExpression: Set<string> = new Set();
+
   constructor(
     public legendService: LegendService,
     public networkHandler: NetworkHandlerService,
@@ -448,6 +450,7 @@ export class NetworkComponent implements OnInit {
 
   public selectTissue(tissue: Tissue | null) {
     this.loadingScreen.stateUpdate(true);
+    this.nodeGroupsWithExpression = new Set();
     this.expressionExpanded = false;
     if (!tissue) {
       // delete expression values
@@ -516,6 +519,7 @@ export class NetworkComponent implements OnInit {
           const networkIdMapping = {};
           this.nodeData.nodes.get().forEach(element => {
             if (element.drugstoneType === 'protein') {
+              this.nodeGroupsWithExpression.add(element.group);
               element.drugstoneId.forEach(id => {
                 if (networkIdMapping[id]) {
                   networkIdMapping[id].push(element.id);
diff --git a/src/index.html b/src/index.html
index 3180b42ff030a13587aac4ca6aa5ebf41632d328..dc08e199a74dd9cde978e8917dbbad5f01599de7 100644
--- a/src/index.html
+++ b/src/index.html
@@ -113,9 +113,9 @@ menu<br>
 <div style="max-width: 80vw; width: 1276px; height: 500px">
 
   <drugst-one id="netexp1"
-              config="{'activateNetworkMenuButtonAdjacentDisorders':false,'activateNetworkMenuButtonAdjacentDrugs':true, 'activateNetworkMenuButtonAdjacentDisordersDrugs': true, 'licensedDatasets':true}"
+              config="{'activateNetworkMenuButtonAdjacentDisorders':false,'activateNetworkMenuButtonAdjacentDrugs':false, 'activateNetworkMenuButtonAdjacentDisordersDrugs': false, 'licensedDatasets':true}"
               groups='{"nodeGroups":{"important":{"type":"gene","color":"#ff881f","font":{"color":"#000000"},"groupName":"Important Gene","shape":"star"},"gene":{"type":"gene","color":"#4da300","font":{"color":"#f0f0f0"},"groupName":"Gene","shape":"circle"},"foundDrug":{"type":"drug","color":"#F12590","font":{"color":"#000000"},"groupName":"Drug","shape":"diamond"}},"edgeGroups":{"default":{"color":"#000000","groupName":"default edge"}}}'
-              network='{"nodes":[{"id":"CFTR","group":"gene","label":"CFTR"},{"id":"TGFB1","group":"gene","label":"TGFB1"},{"id":"TNFRSF1A","group":"gene","label":"TNFRSF1A"},{"id":"FCGR2A","group":"gene","label":"FCGR2A"},{"id":"ENG","group":"gene","label":"ENG"},{"id":"DCTN4","group":"gene","label":"DCTN4"},{"id":"CLCA4","group":"gene","label":"CLCA4"},{"id":"STX1A","group":"gene","label":"STX1A"},{"id":"SCNN1G","group":"gene","label":"SCNN1G"},{"id":"SCNN1A","group":"gene","label":"SCNN1A"},{"id":"SCNN1B","group":"gene","label":"SCNN1B"}],"edges":[{"from":"DCTN4","to":"CFTR"},{"from":"STX1A","to":"SCNN1B","group":"default"},{"from":"SCNN1A","to":"SCNN1G","group":"default"},{"from":"SCNN1B","to":"SCNN1G","group":"default"}]}'>
+              network='{"nodes":[{"id":"CFTR","group":"important","label":"CFTR"},{"id":"TGFB1","group":"gene","label":"TGFB1"},{"id":"TNFRSF1A","group":"gene","label":"TNFRSF1A"},{"id":"FCGR2A","group":"gene","label":"FCGR2A"},{"id":"ENG","group":"gene","label":"ENG"},{"id":"DCTN4","group":"gene","label":"DCTN4"},{"id":"CLCA4","group":"gene","label":"CLCA4"},{"id":"STX1A","group":"gene","label":"STX1A"},{"id":"SCNN1G","group":"gene","label":"SCNN1G"},{"id":"SCNN1A","group":"gene","label":"SCNN1A"},{"id":"SCNN1B","group":"gene","label":"SCNN1B"}],"edges":[{"from":"DCTN4","to":"CFTR"},{"from":"STX1A","to":"SCNN1B","group":"default"},{"from":"SCNN1A","to":"SCNN1G","group":"default"},{"from":"SCNN1B","to":"SCNN1G","group":"default"}]}'>
     ></drugst-one>
 
   <!--  <drugst-one id="netexp1"-->