The Standalone tab provides a basic and unspecified version of the Drugst.One
plugin. For once it is a demonstration how Drugst.One can be integrated and
basic functions and networks can be tested here before or instead of
integrating it into an own website.
To add nodes, simply add a list of nodeIds in the left box. These can be
separated by tabulator, newline, comma, semicolon or space. Also they have to
fit the selected ID source. Accepted types are Symbols, Ensembl IDs or UniProt
Accession numbers. For now the IDs are also case sensitive, so non numeric
characters are most times written as uppercase letters. All nodes are added to
the default Gene node group.
Edges can be defined by entering a newline separated list of node id pairs in
the right text input field. The node ids can be again separated by tabulator,
comma, semicolon or space. All entries are added to the group of
default edges.
Some additional options for basic network configuration are available in the
Advanced panel. For once the source of internally used datasets for
protein protein interaction (PPI) and drug protein interaction (DPI)
information can be selected.
For PPIs we have STRING,
BioGrid and
APID to select from.
STRING is the default dataset.
For DPIs there are
DrugBank,
ChEML and
DGIdb. Here also the
first option, DrugBank is the default selection.
Further there is an option to allow Drugst.One to add all missing interaction
edges, based of course on the selected PPI datasource. By
default this option is enabled.