The Standalone tab provides a basic and unspecified version of the Drugst.One plugin. For once it is a demonstration how Drugst.One can be integrated and basic functions and networks can be tested here before or instead of integrating it into an own website. To add nodes, simply add a list of nodeIds in the left box. These can be separated by tabulator, newline, comma, semicolon or space. Also they have to fit the selected ID source. Accepted types are Symbols, Ensembl IDs or UniProt Accession numbers. For now the IDs are also case sensitive, so non numeric characters are most times written as uppercase letters. All nodes are added to the default Gene node group. Edges can be defined by entering a newline separated list of node id pairs in the right text input field. The node ids can be again separated by tabulator, comma, semicolon or space. All entries are added to the group of default edges. Some additional options for basic network configuration are available in the Advanced panel. For once the source of internally used datasets for protein protein interaction (PPI) and drug protein interaction (DPI) information can be selected.
For PPIs we have STRING, BioGrid and APID to select from. STRING is the default dataset.
For DPIs there are DrugBank, ChEML and DGIdb. Here also the first option, DrugBank is the default selection.
Further there is an option to allow Drugst.One to add all missing interaction edges, based of course on the selected PPI datasource. By default this option is enabled.