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<!doctype html>
<html lang="en">
<head>
<meta charset="utf-8">
<title>Network Expander</title>
<!-- <base href="/">-->
<!-- <meta name="viewport" content="width=device-width, initial-scale=1.0">-->
<!-- <script type="text/javascript" src="https://unpkg.com/vis-network/standalone/umd/vis-network.min.js"></script>-->
<script src="https://cdn.drugst.one/v1.0.9-rc6/prod/drugstone.js"></script>
<link rel="stylesheet" href="https://cdn.drugst.one/v1.0.9-rc6/prod/styles.css">
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</head>
<body>
<input type="checkbox" onclick=changeConfigStr('{"showOverview":'+this.checked+'}') checked /> Show overview<br>
<input type="checkbox" onclick=changeConfigStr('{"showQuery":'+this.checked+'}') /> Show query<br>
<!-- <input type="checkbox" onclick=changeConfigStr('{"showSidebar":'+this.checked+'}') checked /> Show sidebar<br> -->
<input type="checkbox" onclick=changeConfigStr('{"showItemSelector":'+this.checked+'}') checked /> Show ItemSelector<br>
<input type="checkbox" onclick=changeConfigStr('{"showSimpleAnalysis":'+this.checked+'}') /> Show SimpleAnalysis<br>
<input type="checkbox" onclick=changeConfigStr('{"showAdvAnalysis":'+this.checked+'}') checked /> Show Advanced Analysis<br>
<input type="checkbox" onclick=changeConfigStr('{"showTasks":'+this.checked+'}') checked /> Show Tasks<br>
<input type="checkbox" onclick=changeConfigStr('{"showSelection":'+this.checked+'}') checked /> Show Selection<br>
<input type="checkbox" onclick=changeConfigStr('{"showNetworkMenu":'+this.checked+'}') checked /> Show Footer<br>
<input type="checkbox" onclick=changeConfigStr('{"showLegend":'+this.checked+'}') checked /> Show Legend<br>
<input type="checkbox" onclick=changeConfigStr('{"showNetworkMenuButtonScreenshot":'+this.checked+'}') checked /> Show Screenshot button<br>
<input type="checkbox" onclick=changeConfigStr('{"showNetworkMenuButtonExportGraphml":'+this.checked+'}') checked /> Show Export As Graphml Button<br>
<input id="new_color" type="text" /> <button onclick=changeColor(document.getElementById("new_color").value) >Set Color </button> <br>
<button onclick=changeConfigStr('{"legendPos":"left"}') > Legend to Left </button> <br>
<button onclick=changeConfigStr('{"legendPos":"right"}') > Legend to Right </button> <br>
<button onclick=changeConfigStr('{"interactions":"omnipath"}') >Get Omnipath Interactions </button> <br>
<button onclick=changeConfigStr('{"showSidebar":false}') > Hide sidebar</button><br>
<button onclick=changeConfigStr('{"showSidebar":"left"}') > Mode sidebar to left</button><br>
<button onclick=changeConfigStr('{"showSidebar":"right"}') > Move sidebar to right</button><br>
<button onclick=changeConfigStr('{"showNetworkMenu":false}') > Hide networkMenu</button><br>
<button onclick=changeConfigStr('{"showNetworkMenu":"left"}') > Mode networkMenu to left</button><br>
<button onclick=changeConfigStr('{"showNetworkMenu":"right"}') > Move networkMenu to right</button><br>
<button onclick="initTaskEventListener()">Init Task-Eventlistener</button> <br>
<input id="taskID" type="text" /> <button onclick=loadTaskID(document.getElementById("taskID").value) class="button is-primary" >Load TaskID</button> <br>
<br>
<br>
<b>Datasets</b>
<div>
<i>Protein-Protein Interactions</i>
<select name="Protein-Protein Interactions" onchange="applyDataset()" id="ppi-dataset">
<option value="NeDRex">NeDRex</option>
<option value="BioGRID">BioGRID</option>
<option value="IID">IID</option>
<option value="IntAct">IntAct</option>
<option value="STRING">STRING</option>
<option value="APID">APID</option>
</select>
</div>
<div>
<i>Drug-Protein Targets</i>
<select name="Drug-Protein Targets" onchange="applyDataset()" id="drpi-dataset">
<option value="NeDRex">NeDRex</option>
<option value="DrugBank">DrugBank</option>
<option value="Drug Central">Drug Central</option>
<option value="ChEMBL">ChEMBL</option>
<option value="DGIdb">DGIdb</option>
</select>
</div>
<div>
<i>Drug-Disorder Indications</i>
<select name="Drug-Disorder Indications" onchange="applyDataset()" id="drdi-dataset">
<option value="NeDRex">NeDRex</option>
<option value="CTD">CTD</option>
<option value="Drug Central">Drug Central</option>
<option value="DrugBank">DrugBank</option>
</select>
</div>
<div>
<i>Protein-Disorder Associations</i>
<select name="Protein-Disorder Associations" onchange="applyDataset()" id="pdis-dataset">
<option value="NeDRex">NeDRex</option>
<option value="DisGeNET">DisGeNET</option>
<option value="omim">OMIM</option>
</select>
</div>
<!--<input type="checkbox" onclick=changeConfigStr('{"showSimpleAnalysis":'+this.checked+'}') checked /> Show SimpleAnalysis<br>-->
<br>
<button onclick="setNetwork('netexp1')">Add nodes</button>
<div style="max-width: 80vw">
<drugst-one id="netexp1"
pluginId="2"
config='{"interactionDrugProtein":"NeDRex", "physicsOn":true, "showLeftSidebar": true, "showSimpleAnalysis":true, "nodeGroups":{"patient":{"type":"patient","color":"black","font":{"color":"#ffffff"},"groupName":"Patient","shape":"image","image":"https://static.thenounproject.com/png/22780-200.png"},"condition":{"type":"condition","color":"black","font":{"color":"black"},"groupName":"Condition","shape":"text"},"important":{"type":"gene","color":"#ff881f","font":{"color":"#000000"},"groupName":"Important Gene","shape":"star"},"gene":{"type":"gene","color":"#4da300","font":{"color":"#ffffff"},"groupName":"Gene","shape":"circle"},"foundDrug":{"type":"drug","color":{"border":"#F12590","background":"#F12590"},"font":{"color":"#f0f0f0"},"groupName":"Drug","shape":"diamond"}},"edgeGroups":{"genotype":{"color":"black","groupName":"Relevant Gene"},"has-condition":{"color":"#000000","groupName":"Has Condition","dashes":[2,2]},"default":{"color":"#000000","groupName":"default edge"},"ggi":{"color":"#000000","groupName":"Interaction","dashes":[3,2]}},"identifier":"symbol","title":"Breast cancer example network","nodeShadow":true,"edgeShadow":false,"autofillEdges":true,"showLegend":true}'
network='{"nodes":[{"id":"patient-1","group":"patient","x":592,"y":446},{"id":"patient-2","group":"patient","x":235,"y":87},{"id":"patient-3","group":"patient","x":105,"y":369},{"id":"ATM","label":"ATM","group":"gene","x":289,"y":242},{"id":"BARD1","label":"BARD1","group":"gene","x":44,"y":250},{"id":"BRCA1","label":"BRCA1","group":"gene","x":466,"y":576},{"id":"BRCA2","label":"BRCA2","group":"gene","x":507,"y":285},{"id":"BRIP1","label":"BRIP1","group":"gene","x":54,"y":474},{"id":"CHEK2","label":"CHEK2","group":"gene","x":216,"y":590},{"id":"CDH1","label":"CDH1","group":"gene","x":320,"y":-57},{"id":"NF1","label":"NF1","group":"gene","x":481,"y":111},{"id":"NBN","label":"NBN","group":"gene","x":-57,"y":314},{"id":"PALB2","label":"PALB2","group":"gene","x":450,"y":190},{"id":"PTEN","label":"PTEN","group":"important","x":305,"y":494},{"id":"RAD51C","label":"RAD51C","group":"gene","x":182,"y":-90},{"id":"RAD51D","label":"RAD51D","group":"gene","x":368,"y":73},{"id":"STK11","label":"STK11","group":"gene","x":686,"y":330},{"id":"TP53","label":"TP53","group":"important","x":333,"y":316},{"id":"subtype-1","label":"Subtype 1","group":"condition","x":556,"y":171},{"id":"subtype-2","label":"Subtype 2","group":"condition","x":-87,"y":221}],"edges":[{"from":"BRCA1","to":"BRCA2","group":"ggi"},{"from":"ATM","to":"BARD1","group":"ggi"},{"from":"BRCA1","to":"CHEK2","group":"ggi"},{"from":"RAD51C","to":"RAD51D","group":"ggi"},{"from":"STK11","to":"TP53","group":"ggi"},{"from":"TP53","to":"PALB2","group":"ggi"},{"from":"TP53","to":"RAD51D","group":"ggi"},{"from":"TP53","to":"NF1","group":"ggi"},{"from":"TP53","to":"BRCA1","group":"ggi"},{"from":"TP53","to":"BRCA2","group":"ggi"},{"from":"PTEN","to":"BRCA1","group":"ggi"},{"from":"PTEN","to":"BRCA2","group":"ggi"},{"from":"TP53","to":"PTEN","group":"ggi"},{"from":"ATM","to":"PTEN","group":"ggi"},{"from":"CDH1","to":"RAD51D","group":"ggi"},{"from":"CDH1","to":"PALB2","group":"ggi"},{"from":"NBN","to":"BRIP1","group":"ggi"},{"from":"BRIP1","to":"PTEN","group":"ggi"},{"from":"patient-1","to":"BRCA1","group":"genotype"},{"from":"patient-1","to":"TP53","group":"genotype"},{"from":"patient-1","to":"BRCA2","group":"genotype"},{"from":"patient-1","to":"PTEN","group":"genotype"},{"from":"patient-2","to":"TP53","group":"genotype"},{"from":"patient-2","to":"NF1","group":"genotype"},{"from":"patient-2","to":"BARD1","group":"genotype"},{"from":"patient-3","to":"TP53","group":"genotype"},{"from":"patient-3","to":"PTEN","group":"genotype"},{"from":"patient-3","to":"NBN","group":"genotype"},{"from":"patient-1","to":"subtype-1","group":"has-condition"},{"from":"patient-2","to":"subtype-1","group":"has-condition"},{"from":"patient-3","to":"subtype-2","group":"has-condition"}]}'>
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</drugst-one>
</div>
<!--<div >-->
<!-- <network-expander id="netexp2"-->
<!-- pluginId="2"-->
<!-- config='{}' network='{"nodes":[], "edges":[]}'></network-expander>-->
<!--</div>-->
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<script>
function changeConfig() {
const netexp = document.getElementById('netexp1');
netexp.setAttribute('config', '{"showLeftSidebar": false}');
}
function changeConfigStr(config) {
console.log(config);
const netexp = document.getElementById('netexp1');
netexp.setAttribute('config', config);
}
function initTaskEventListener(){
document.getElementsByTagName("drugst-one")[0].addEventListener("taskEvent",(event)=>{console.log(event.detail)})
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}
function applyDataset(){
let ppi = document.getElementById('ppi-dataset')
setDataset('interactionProteinProtein',ppi.options[ppi.selectedIndex].value)
let drpi = document.getElementById('drpi-dataset')
setDataset('interactionDrugProtein', drpi.options[drpi.selectedIndex].value)
let drdi = document.getElementById('drdi-dataset')
setDataset('indicationDrugDisorder', drdi.options[drdi.selectedIndex].value)
let pdis = document.getElementById('pdis-dataset')
setDataset('associatedProteinDisorder', pdis.options[pdis.selectedIndex].value)
}
function setDataset(name, dataset){
// console.log(event)
console.log("Dataset "+name+" -> "+dataset)
const netexp = document.getElementById('netexp1');
config = JSON.parse(netexp.getAttribute('config'))
console.log(config)
config[name]=dataset
changeConfigStr(JSON.stringify(config))
}
function setNetwork(nw) {
const netexp = document.getElementById(nw);
netexp.setAttribute('network', JSON.stringify({
nodes: [
{
name: "ENSG00000171862",
id: "ENSG00000171862",
group: "genes"
}
],
edges: [
]
}));
}
function changeColor(hexacode) {
console.log(hexacode)
const elements_background_color = document.getElementsByClassName('is-primary');
for(var i = 0; i < elements_background_color.length; i++){
elements_background_color[i].setAttribute('style', `background-color: ${hexacode} !important; color: white !important; border-color: ${hexacode} !important`);
}
const elements_text = document.getElementsByClassName('text-primary');
for(var i = 0; i < elements_text.length; i++){
elements_text[i].setAttribute('style', `color: ${hexacode} !important`);
}
}
function loadTaskID(token){
console.log("Trying to load "+token)
const netexp = document.getElementById('netexp1');
netexp.setAttribute('task-id', token);
}
</script>
</body>
</html>