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index.html 28.01 KiB
<!doctype html>
<html lang="en">
<head>
<meta charset="utf-8">
<title>Network Expander</title>
<base href="/">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<script type="text/javascript" src="https://unpkg.com/vis-network/standalone/umd/vis-network.min.js"></script>
<!-- <link rel="stylesheet" type="text/css" href="./stylesheets/default-theme.css">-->
</head>
<body>
<input type="checkbox" onclick=changeConfigStr('{"showOverview":'+this.checked+'}') checked /> Show overview<br>
<input type="checkbox" onclick=changeConfigStr('{"showQuery":'+this.checked+'}') /> Show query<br>
<input type="checkbox" onclick=changeConfigStr('{"showItemSelector":'+this.checked+'}') checked /> Show ItemSelector<br>
<input type="checkbox" onclick=changeConfigStr('{"showConnectGenes":'+this.checked+'}') /> Show Connect Genes<br>
<input type="checkbox" onclick=changeConfigStr('{"showSimpleAnalysis":'+this.checked+'}') checked /> Show Simple Analysis<br>
<input type="checkbox" onclick=changeConfigStr('{"showAdvAnalysis":'+this.checked+'}') checked /> Show Advanced Analysis<br>
<input type="checkbox" onclick=changeConfigStr('{"showTasks":'+this.checked+'}') checked /> Show Tasks<br>
<input type="checkbox" onclick=changeConfigStr('{"showSelection":'+this.checked+'}') checked /> Show Selection<br>
<input type="checkbox" onclick=changeConfigStr('{"showNetworkMenu":'+this.checked+'}') checked /> Show Footer<br>
<input type="checkbox" onclick=changeConfigStr('{"showLegend":'+this.checked+'}') checked /> Show Legend<br>
<input type="checkbox" onclick=changeConfigStr('{"showNetworkMenuButtonScreenshot":'+this.checked+'}') checked /> Show Screenshot button<br>
<input type="checkbox" onclick=changeConfigStr('{"showNetworkMenuButtonExportGraphml":'+this.checked+'}') checked /> Show Export As Graphml Button<br>
<input id="new_color" type="text" /> <button onclick=changeColor(document.getElementById("new_color").value) >Set Color </button> <br>
<button onclick=changeConfigStr('{"legendPos":"left"}') > Legend to Left </button> <br>
<button onclick=changeConfigStr('{"legendPos":"right"}') > Legend to Right </button> <br>
<button onclick=changeConfigStr('{"interactions":"omnipath"}') >Get Omnipath Interactions </button> <br>
<button onclick=changeConfigStr('{"showSidebar":false}') > Hide sidebar</button><br>
<button onclick=changeConfigStr('{"showSidebar":"left"}') > Mode sidebar to left</button><br>
<button onclick=changeConfigStr('{"showSidebar":"right"}') > Move sidebr to right</button><br>
<button onclick=changeConfigStr('{"showNetworkMenu":false}') > Hide networkMenu</button><br>
<button onclick=changeConfigStr('{"showNetworkMenu":"left"}') > Mode networkMenu to left</button><br>
<button onclick=changeConfigStr('{"showNetworkMenu":"right"}') > Move networkMenu to right</button><br>
<button onclick="initTaskEventListener()">Init Task-Eventlistener</button> <br>
<input id="taskID" type="text" /> <button onclick=loadTaskID(document.getElementById("taskID").value) class="button is-primary" >Load TaskID</button> <br>
<br>
<br>
<b>Datasets</b>
<input type="checkbox" onclick=changeLicenced(this.checked) /> Use licenced datasets<br>
<div>
<i>Protein-Protein Interactions</i>
<select name="Protein-Protein Interactions" onchange="applyDataset()" id="ppi-dataset">
<option value="NeDRex">NeDRex</option>
<option value="STRING">STRING</option>
<option value="biogrid">BioGRID</option>
<option value="iid">IID</option>
<option value="IntAct">IntAct</option>
<option value="APID">APID</option>
</select>
</div>
<div>
<i>Drug-Protein Targets</i>
<select name="Drug-Protein Targets" onchange="applyDataset()" id="drpi-dataset">
<option value="NeDRex">NeDRex</option>
<option value="DrugBank">DrugBank</option>
<option value="Drug Central">Drug Central</option>
<option value="ChEMBL">ChEMBL</option>
<option value="DGIdb">DGIdb</option>
</select>
</div>
<div>
<i>Drug-Disorder Indications</i>
<select name="Drug-Disorder Indications" onchange="applyDataset()" id="drdi-dataset"> <option value="NeDRex">NeDRex</option>
<option value="CTD">CTD</option>
<option value="Drug Central">Drug Central</option>
<option value="DrugBank">DrugBank</option>
</select>
</div>
<div>
<i>Protein-Disorder Associations</i>
<select name="Protein-Disorder Associations" onchange="applyDataset()" id="pdis-dataset">
<option value="NeDRex">NeDRex</option>
<option value="DisGeNET">DisGeNET</option>
<option value="omim">OMIM</option>
</select>
</div>
<!--<input type="checkbox" onclick=changeConfigStr('{"showSimpleAnalysis":'+this.checked+'}') checked /> Show SimpleAnalysis<br>-->
<br>
<button onclick="setNetwork('netexp1')">Add nodes</button>
<div style="max-width: 80vw; width: 1276px; height: 500px">
<drugst-one id="netexp1"
pluginId="2"
groups='{"nodeGroups":{"important":{"type":"gene","color":"#ff881f","font":{"color":"#000000"},"groupName":"Seed","shape":"star"},"gene":{"type":"gene","color":"#4da300","font":{"color":"#f0f0f0"},"groupName":"Discovered target","shape":"circle"},"foundDrug":{"type":"drug","color":"#F12590","font":{"color":"#000000"},"groupName":"Drug","shape":"diamond"}},"edgeGroups":{"default":{"color":"#000000","groupName":"default edge"}}}'
config='{ "identifier":"symbol","title":"ROBUST output network", "taskDrugName": "Drug Search", "showLegendNodes": true, "showLegendEdges": true, "showSidebar": "left", "showOverview": true, "legendPos": "left", "legendClass": "legend", "showQuery": true, "showItemSelector": true,"showSimpleAnalysis": false,"showAdvAnalysis": true,"showSelection": true,"showTasks": true,"showNetworkMenu": "right","showLegend": true,"showNetworkMenuButtonExpression": true, "showNetworkMenuButtonScreenshot": true,"showNetworkMenuButtonExportGraphml": true,"showNetworkMenuButtonAdjacentDrugs": true,"showNetworkMenuButtonCenter": true,"showConnectGenes": false,"networkMenuButtonAdjacentDrugsLabel": "Drugs","showNetworkMenuButtonAdjacentDisordersProteins": true,"networkMenuButtonAdjacentDisordersProteinsLabel": "Disorders (protein)","showNetworkMenuButtonAdjacentDisordersDrugs": true,"networkMenuButtonAdjacentDisordersDrugsLabel": "Disorders (drug)","showNetworkMenuButtonAnimation": true,"networkMenuButtonAnimationLabel": "Animation", "autofillEdges": false, "physicsOn": false,"useNedrexLicenced": true,"selfReferences": false, "interactionDrugProtein": "NeDRex", "indicationDrugDisorder": "NeDRex","nodeShadow": true,"edgeShadow": true, "algorithms": {"drug": ["trustrank", "closeness", "degree", "proximity"], "drug-target": ["trustrank", "multisteiner", "keypathwayminer", "degree", "closeness", "betweenness"]}, "associatedProteinDisorder": "NeDRex", "expandNetworkMenu": true}'
network='{"nodes": [{"id": "UBE2I", "group": "gene"}, {"id": "EEF1A1", "group": "gene"}, {"id": "KDM5A", "group": "gene"}, {"id": "THOC2", "group": "gene"}, {"id": "XPO1", "group": "gene"}, {"id": "RPL4", "group": "gene"}, {"id": "TOP1", "group": "gene"}, {"id": "YWHAE", "group": "gene"}, {"id": "CHUK", "group": "gene"}, {"id": "HSP90AB1", "group": "gene"}, {"id": "CD6", "group": "important"}, {"id": "TYK2", "group": "important"}, {"id": "FSTL1", "group": "gene"}, {"id": "CBL", "group": "gene"}, {"id": "NR2F2", "group": "gene"}, {"id": "RUNX1T1", "group": "gene"}, {"id": "MED23", "group": "gene"}, {"id": "IFNAR1", "group": "gene"}, {"id": "LCOR", "group": "gene"}, {"id": "IL10", "group": "important"}, {"id": "NLRP3", "group": "important"}, {"id": "A2M", "group": "gene"}, {"id": "EIF4A1", "group": "gene"}, {"id": "HSPA4", "group": "gene"}, {"id": "ACTB", "group": "gene"}, {"id": "SNRPB", "group": "gene"}, {"id": "KIF1B", "group": "important"}, {"id": "HIST1H1B", "group": "gene"}, {"id": 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"gene"}, {"id": "COL14A1", "group": "gene"}, {"id": "YWHAG", "group": "gene"}, {"id": "MS4A1", "group": "gene"}, {"id": "SF1", "group": "gene"}, {"id": "CASP10", "group": "gene"}, {"id": "TP53", "group": "gene"}, {"id": "GC", "group": "important"}, {"id": "TRAF6", "group": "gene"}, {"id": "CASP1", "group": "important"}], "edges": [{"from": "UBE2I", "to": "KIF1B", "group": "default"}, {"from": "UBE2I", "to": "TNFRSF1A", "group": "default"}, {"from": "EEF1A1", "to": "VCAM1", "group": "default"}, {"from": "EEF1A1", "to": "KIF1B", "group": "default"}, {"from": "KDM5A", "to": "RBPJ", "group": "default"}, {"from": "KDM5A", "to": "VDR", "group": "default"}, {"from": "THOC2", "to": "VCAM1", "group": "default"}, {"from": "THOC2", "to": "KIF1B", "group": "default"}, {"from": "XPO1", "to": "RBPJ", "group": "default"}, {"from": "XPO1", "to": "VCAM1", "group": "default"}, {"from": "XPO1", "to": "RAP1GAP", "group": "default"}, {"from": "RPL4", "to": "APOE", "group": "default"}, {"from": "RPL4", 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