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<h1 class="title">About CoVex</h1>
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<h2 class="subtitle is-3"> A Coronavirus Explorer </h2>
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<br>
CoVex (Coronavirus Explorer) is a unique online network and systems medicine platform for data analysis that
integrates virus-human interactions for SARS-CoV-2 and SARS-CoV-1. It implements different network-based
approaches for the identification of new drug targets and new repurposable drugs.<br>
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For instructions and help check the documentation:
<a href="https://docs.google.com/document/d/1_SRnIx_UC8FR59rMyrf_r45fCIt3naP4t1qefYNp9vk">CoVex Documentation</a><br>
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We are constantly updating and integrating new data as it becomes available.
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If you are interested to make your virus-human interactome data available via our platform, please contact
us.
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<h2 class="subtitle">Read our blog</h2>
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For detailed information on CoVex and the development process please visit our blog:
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<li><a href="https://www.exbio.de/exbio-vs-covid-part-1/">ExBio vs Covid - Part 1</a></li>
<li><a href="https://www.exbio.de/exbio-vs-covid-part-2/">ExBio vs Covid - Part 2</a></li>
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<h2 class="subtitle">General workflow of the platform</h2>
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<li>Select the viral interaction dataset (SARS-CoV1-Pfefferle, SARS-CoV1-VirHostNet, SARS-CoV2-Gordon).</li>
<li>Select proteins of interest as seed proteins.</li>
<li>Perform network analysis (multi-Steiner, TrustRank, KeyPathwayMiner, closeness centrality).</li>
<li>Platform usage: basic and advanced options</li>
<li>Inspect the resulting subnetworks.</li>
<li>Find drugs associated with the subnetwork (TrustRank, closeness centrality).</li>
<li>Download your results.</li>
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<p>CoVex also provides a quick analysis option to perform steps 3 to 5 (starting from the seed proteins) to
return
a list of drugs ranked by default using TrustRank.</p>
<h2>Help/Contact information</h2>
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<li>General support and inquiries: CoVex dev team (covex_AT_wzw.tum.de)</li>
<li>Systems and network medicine: Sepideh Sadegh (sadegh_AT_wzw.tum.de)</li>
<li>Web platform: Julian Matschinske (julian.matschinske_AT_wzw.tum.de)</li>
<li>Project coordination: Prof. Dr. Jan Baumbach (jan.baumbach_AT_wzw.tum.de)</li>
<li>Lab website: <a href="http://www.exbio.de">http://www.exbio.de</a></li>
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<h2 class="subtitle"> Impressum</h2>
<p>Prof. Dr. Jan Baumbach
Chair of Experimental Bioinformatics
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<i class="fa fa-phone"></i> Phone: +49-8161-71-2136<br>
<i class="fa fa-phone"></i> Fax: +49-8161-71-2186<br>
<i class="fa fa-envelope"> </i> Email: exbio_AT_wzw.tum.de<br>
<i class="fa fa-map-marker"></i> Address: Prof. Dr. Jan Baumbach
<br>
Chair of Experimental Bioinformatics
<br>
TUM School of Life Sciences Weihenstephan
<br>
Technical University of Munich<br>
Maximus-von-Imhof-Forum 3<br>
85354 Freising<br>
Germany </p>
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