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about-page.component.html

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    about-page.component.html 4.00 KiB
    <div class="scroll">
      <div class="content">
        <section class="hero is-primary">
          <div class="hero-body">
            <div class="container">
              <h1 class="title">About CoVex</h1>
            </div>
          </div>
        </section>
    
        <div class="hero container">
          <div class="column is-8 is-offset-2">
            <div class="container has-text-centered">
              <img src="assets/covex_logo.png">
              <h2 class="subtitle is-3"> A Coronavirus Explorer </h2>
            </div>
            <div class="content">
              <p>
                <br>
                CoVex (Coronavirus Explorer) is a unique online network and systems medicine platform for data analysis that
                integrates virus-human interactions for SARS-CoV-2 and SARS-CoV-1. It implements different network-based
                approaches for the identification of new drug targets and new repurposable drugs.<br>
                <br>
                For instructions and help check the documentation:
                <a href="https://docs.google.com/document/d/1_SRnIx_UC8FR59rMyrf_r45fCIt3naP4t1qefYNp9vk">CoVex Documentation</a><br>
                <br>
                We are constantly updating and integrating new data as it becomes available.
                <br>
                If you are interested to make your virus-human interactome data available via our platform, please contact
                us.
              </p>
              <h2 class="subtitle">Read our blog</h2>
              <p>
                For detailed information on CoVex and the development process please visit our blog:
              </p>
              <ul>
                <li><a href="https://www.exbio.de/exbio-vs-covid-part-1/">ExBio vs Covid - Part 1</a></li>
                <li><a href="https://www.exbio.de/exbio-vs-covid-part-2/">ExBio vs Covid - Part 2</a></li>
              </ul>
              <h2 class="subtitle">General workflow of the platform</h2>
              <ol>
                <li>Select the viral interaction dataset (SARS-CoV1-Pfefferle, SARS-CoV1-VirHostNet, SARS-CoV2-Gordon).</li>
                <li>Select proteins of interest as seed proteins.</li>
                <li>Perform network analysis (multi-Steiner, TrustRank, KeyPathwayMiner, closeness centrality).</li>
                <li>Platform usage: basic and advanced options</li>
                <li>Inspect the resulting subnetworks.</li>
                <li>Find drugs associated with the subnetwork (TrustRank, closeness centrality).</li>
                <li>Download your results.</li>
              </ol>
              <p>CoVex also provides a quick analysis option to perform steps 3 to 5 (starting from the seed proteins) to
                return
                a list of drugs ranked by default using TrustRank.</p>
              <h2>Help/Contact information</h2>
              <ul>
                <li>General support and inquiries: CoVex dev team (covex_AT_wzw.tum.de)</li>
                <li>Systems and network medicine: Sepideh Sadegh (sadegh_AT_wzw.tum.de)</li>
                <li>Web platform: Julian Matschinske (julian.matschinske_AT_wzw.tum.de)</li>
                <li>Project coordination: Prof. Dr. Jan Baumbach (jan.baumbach_AT_wzw.tum.de)</li>
                <li>Lab website: <a href="http://www.exbio.de">http://www.exbio.de</a></li>
              </ul>
    
              <br>
              <br>
    
              <div class="has-text-centered">
                <h2 class="subtitle"> Impressum</h2>
                <p>Prof. Dr. Jan Baumbach
                  Chair of Experimental Bioinformatics
                  <br>
                  <i class="fa fa-phone"></i> Phone: +49-8161-71-2136<br>
                  <i class="fa fa-phone"></i> Fax: +49-8161-71-2186<br>
                  <i class="fa fa-envelope"> </i> Email: exbio_AT_wzw.tum.de<br>
                  <i class="fa fa-map-marker"></i> Address: ​​​Prof. Dr. Jan Baumbach
                  <br>
                  Chair of Experimental Bioinformatics
                  <br>
                  TUM School of Life Sciences Weihenstephan
                  <br>
                  Technical University of Munich<br>
                  Maximus-von-Imhof-Forum 3<br>
                  85354 Freising<br>
                  Germany </p>
              </div>
            </div>
          </div>
        </div>
      </div>
    </div>